Ancona - a city on Italy’s Adriatic coast and the capital of the Marche region. It’s known for beaches, such as Passetto Beach, and the hilltop Cathedral of San Ciriaco.
Ascoli Piceno - Piazza del Popolo, an elegant Renaissance square in the center, and the 13th-century Palazzo dei Capitani del Popolo is a palace built over Roman ruins. The Civic Picture Gallery, decorated with Murano glass chandeliers, displays paintings by Titian and Carlo Crivelli.
Urbino - a walled city in central Italy. It's known for the turreted, 15th-century Palazzo Ducale. Inside the palace, the National Gallery of the Marche features paintings by Titian and Raphael, who was born in the town. This is one of the main cities in Marche and well worth a visit.
Macerata - a university town with a Renaissance atmosphere.
Pesaro - is a unique city with featrues that make it a great place for tourist interests. There is the ancient city with its prestigious historical centre, but also it is one of the most famous seaside resorts of the Adriatic coast.
The independent republic of San Marino is to the north of the region - always crowded but interesting to visit the for the citadel at the top of the hill - even just to say you have visited another country !